(855) 339-8879

Actos Lawsuit Attorney

The unsafe drug interaction attorneys at the DTLA Law Group are now accepting cases for the type 2 diabetes drug.  Actos (pioglitazone) was approved by the Food and Drug Administration (FDA) in 1999 to treat Type 2 diabetes. Takeda Pharmaceuticals is the manufacturer of Actos and  is subsidiary of Takeda Pharmaceutical Company Limited, Japan’s largest drug company.  As a result of Takeda’s negligence of Actos’s defective design, manufacturing, and testing, persons who took Actos for more than a year were at increased risk for developing serious injuries including bladder cancer. Thousands of lawsuits have already been filed against Takeda alleging that the makers of Actos failed to warn and concealed their knowledge about the nature and extent of the drug’s risks

What is Actos

Actos is a pharmaceutical drug used to control blood sugar in patients with type 2 diabetes mellitus. It is in the class of drugs known as peroxisome proliferator-activated receptor (PPAR) agonists. The only other drug in this class is Avandia (rosiglitazone). The FDA has no clinical information associating Avandia with bladder cancer in patients receiving that drug. According to the drug maker’s website, Actos works on “two of the common problems that lead to high blood sugar in type 2 diabetes.” 1. Actos allows your body to better utilize the insulin it produces. 2. It prevents the user’s liver from making additional unnecessary sugar When it was first introduced, Takeda hailed Actos as a miraculous cure for type 2 diabetes.  However, patients soon began developing serious side effects as a result of the drug, including heart failure, macular edema, lactic acidosis, bone fractures and in serious instances, bladder cancer.  Takeda continues to market the drug as safe and effective, even in light of FDA and independent studies that Actos increases the risk of serious injuries.

Actos Linked to Bladder Cancer RIsk

On June 15, 2011, the FDA issued a safety warning indicating that the use of Actos for a period greater than 1 year increases the risk of bladder cancer by over 40%.  The results were part of a 10 year study that that demonstrated elevated risk of bladder cancer, especially for those ingesting higher doses and for a longer period of time. Actos lawsuits and claims from side effectsThat same year, health officials in France and Germany outlawed the use of Actos based on their own research relating Actos to an enhanced risk of bladder cancer.  Signs and symptoms that user’s of Actos should look for bladder cancer are:

  • Unusual urinary patterns including burning, pain, and frequency
  • Blood in Urine
  • Back or abdomen soreness
  • Diminished hunger and body mass
  • Dark yellow, bright red or dark brown urine
  • Urinary tract infections

Bladder cancer is responsible for over 14,000 deaths a year in the United States alone, and more than 70,000 individuals will suffer from the disease a year.

Actos Side Effects

In addition to bladder cancer, our Actos Attorneys have noticed that users experience a host of other side effects.  These complications include: Bladder Cancer– According to the most recent findings, patients who used Actos for more than 1 year had forty percent increased risk of bladder cancer. Further studies have shown that the active ingredient in Actos leads to  83% higher risk for bladder cancer in person taking the medication in comparison individuals who had never taken the drug Heart Attack and General Heart Failure – users should be especially cognizant of increased sweating, swelling or breathing issues.

Liver Problems

Fractures – bone fractures and weak bones and osteoporosis.  According to a Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM) study, postmenopausal woman with diabetes are at an increased risk of bone fractures due to the use of Actos. Edema – Studies found edema for 7.2% of patients treated with Actos and sulfonylureas in contrast to 2.1% of patients on sulfonylureas only. In blend treatment studies with metformin, edema was found in 6.0% of patients on combination therapy compared to 2.5% of patients on metformin only. In combination treatment studies with insulin, edema was discovered in 15.3% of patients on combination therapy compared to 7.0% of patients on insulin only. Renal Kidney Failure – the FDA indicated that there is a potential link to rhabdomyolysis Actos and renal kidney failure.  Warning signals include muscle pain and weakness, fever, nausea and vomiting.

Actos Lawsuits and Litigation

Already, hundreds of patients have filed lawsuits against Takeda as studies have linked Actos to serious and even life threatening injuries including bladder cancer, heart failure and fractured bones.  In July 2012, a U.S. Judicial Panel transferred all federal Actos litigation to a single Louisiana federal court.  This is a centralized federal court known as Multidistrict Litigation (MDL) and assigned number 2299. According to a Bloomberg Businessweek article, the amount of plaintiff’s filing future litigation against Actos’ manufacturer Takeda is estimated to surpass over 100,000 people.  These lawsuits are based in large part to Takeda’s failure to warn it’s patients of the potential risks associated with Actos, most notably bladder cancer.  Takeda counters these accusations with claims that the drug is safe, based on the approval by the FDA.  Worst yet, Takeda continues to stubbornly deny any casual link between their drug and bladder cancer, despite numerous studies to the contrary. Downtown L.A. Law will work with victims adversely affected by the use of Actos to make sure they recover for injuries including past and future medical expenses, pain and suffering and lost income.  Actos is also marketed by U.S. drug manufacturer Eli Lilly & Co., and our attorneys will make sure that they will be held accountable for your injuries.

July 15, 1999 The U.S. Food and Drug Administration (FDA) approves the drug Actos for treatment of type 2 diabetes.  Drug is manufactured by Takeda Pharmaceutical and marketed by Eli Lilly & Co.
October 2000 European Medicines Agency (EMA) approves Actos
August 2007 FDA issues a safety warning that Actos causes serious heart conditions.  FDA requires a “Black Box” warning for all pioglitazone hydrochoride medications such as Actos.
June 2010 Whistleblower Helen Ge alleges that Takeda Pharmaceuticals failed to inform FDA of potential heart complications related to Actos.  Ge files on behalf of the government under the False Claims Act.
June 2011  health officials in France and Germany suspended its use based on the studies showing an increased risk of bladder cancer
August 2011  Results of a 10-year study suggest that taking Actos for periods longer than 12 months may increase the relative risk of developing bladder cancer in any given year by as much as 40 percent
August 2011 First Actos bladder cancer lawsuit filed.

Actos Lawyers

The Actos lawyers at Downtown L.A. Law Group are currently investigating the use of Actos in treating type 2 diabetes.  Our attorneys are here to talk about your case and provide a free evaluation of your case.  Call us today to speak to an attorney immediately.

Generic Name:Pioglitazone HydrochlorideOther Names:
  • Actosplus Met
  • Actosplus Met XR
  • Duetact
  • Pioglitazone
  • Pioglitazone Hydrochloride
  • Choride & Metformin Hydrochloride
FDA Approval:July 15, 1999Manufacturer(s):Eli Lilly & Co.Taveka PharmaceuticalsIntended Use:Type 2 Diabetes Side Effects:
  • Bladder Cancer
  • Heart Complications
  • Edema
  • Bone Fractures
  • Hepatitis
  • Heart Attacks
  • Cardiovascular Harms

Bladder Cancer

Wronful Death

Heart Attack

Kidney Failure


Actos Lawsuit

Over $500 Million Recovered
for Our Clients

Learn More

YOU Deserve the Best
Free Case Review 24/7
You Don’t Pay unless we win
Call 855.385.2529

  • This field is for validation purposes and should be left unchanged.

By submitting this form, you agree to receive telephone calls and text messages at anytime, which include hours outside of business hours (8:00 am PST – 9:00 pm PST). This is so that we may reach you as soon as possible in order to consult on your potential case.

ultimate guide uber lyft accidents

Featured Lawyers


Farid Yaghoubtil, Esq.


Salar Hendizadeh, Esq.

Nina Sargsyan, Esq.


Daniel Azizi, Esq.



YOU Deserve the Best
Free Case Review 24/7
Call 855.339.8879

  • This field is for validation purposes and should be left unchanged.

By submitting this form, you agree to receive telephone calls and text messages at anytime, which include hours outside of business hours (8:00 am PST – 9:00 pm PST). This is so that we may reach you as soon as possible in order to consult on your potential case.


910 S Broadway, Suite 600
Los Angeles, CA 90016
(855) 339-8879

4113 Clinton Ave,
Los Angeles, CA 90004
(855) 339-8879

2005, Eye Street, Suite 4
Bakersfield, CA 93301
(661) 219-7455

3430 Tully Road
Modesto, California 95350
(209) 353-4493

2372 Morse Ave.
Irvine, California 92614
(949) 627-8725

01 West Broadway
San Diego, California 92101
(619) 413-0161

105 N Oxnard Blvd,
Oxnard, CA 93030
(805) 263-4423

1 Sansome St. Suite 3500-11
San Francisco, California 94104

701 E Santa Clara St
Ventura, California 95816

7121 Magnolia Ave
Riverside, California 92504

13782 Bear Valley Rd.
Victorville, California 92392
(760) 563-4384

5588 N Palm Ave
Fresno, California 93704
(559) 556-0227

388 Market St #1300
San Francisco, California 94111
(415) 362-6079

1601 Alhambra Blvd
Sacramento, California 95816
(916) 931-1965

1 Sansome St. Suite 3500-11
San Francisco, California 94104
(650) 651-5006

11900 Biscayne Blvd North
Miami, Florida 33154

4600 Alabama St #C
El Paso, Texas 79930
(915) 201-3865

The information on this website is for general information purposes only. Nothing on this site should be taken as legal advice for any individual case or situation. This information is not intended to create, and receipt or viewing does not constitute, an attorney-client relationship.
Follow Us